Figure 1
Structure of human CENP-E. (a) A front view of CENP-E–MgADP from this study is shown in cartoon representation (stereoview). The P-loop (orange), L5 (green), L9 (light pink), L11 (cyan), ADP and Mg (pink) are shown. (b) The Fo − Fc OMIT map for ADP, Mg2+ and water molecules is depicted. The Fo − Fc OMIT map was calculated with the phases from the model without ADP, Mg2+ and neighboring water molecules and contoured at 3σ. |