Figure 6
Adaptive distance restraints in ISOLDE around the ATP-binding site of PDB entry 6mhz after refitting into the map corresponding to the ATP-free state (PDN entry 6mhu). Each restraint is represented as a cylinder, the thickness of which corresponds to the applied force. Stretching restraints beyond the harmonic region causes their colour to change from green to purple; overly compressed restraints turn yellow (not shown). A demonstration of this scenario is provided in Supplementary Movie S3. |