Figure 6
Guest content and concentration. Shown is a hypothetical unit cell (black square) of the host crystal with 25% host protein (gray, comparable to ds-TrpR crystals) and solvent channel (circle) containing solvent (blue) and guest protein (red). Matching the individual panels, the composition of the solvent channels with solvent or guest protein [%(v/v)], respectively, is given above each panel. The corresponding concentrations of guest protein in the host crystal and fractional guest content Φguest (derived from equation 2) are given below each panel. Note that for simplicity only one unit cell is shown, but the guest content can be extrapolated to a crystal (array of unit cells) when the guest concentration distribution is nearly homogeneous throughout the crystal. |