Figure 1
Crystal structure of CtFDOdegl. The cofactor and the N-acetyl-D-glucosamine units (occupied in at least one of the structures) are shown as sticks with magenta and cyan C atoms, respectively. (a) The yellow and blue secondary-structure elements represent the substrate-binding and the FAD-binding domains, respectively. (b) Side view of CtFDOdegl shown as a Cα trace. The active-site pocket, as calculated with HOLLOW (Ho & Gruswitz, 2008), is displayed as a green surface. The black arrow marks the entrance to the pocket. The molecular graphics were created with PyMOL (Schrödinger). |