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![[Figure 2]](ni5012fig2mag.jpg)
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Figure 2
Sequence alignment of PLpros and PLP2s from coronaviruses: PEDV PLP2 (accession No. AHA38151.1), SADS-CoV PLP2 (accession No. ASK51716.1), PDCoV PLpro (accession No. AIP90485.1) and SARS-CoV-2 PLpro (accession No. QKG86869.1). The residue numbering is based on polyprotein 1a of PEDV. The faded secondary structure above the sequence alignment denotes the secondary structure of the UBL from SARS-CoV-2 PLpro (PDB entry 6w9c; Center for Structural Genomics of Infectious Diseases, unpublished work). The colored secondary structure was calculated by DSSP from experimental data and denotes the catalytic core that was used for crystallization. Residues that form the catalytic triad are denoted by sky blue stars, while the zinc-finger residues are marked by purple circles. |
![[Figure 2]](ni5012fig2.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
