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Figure 3
Comparison of the binding of fatty acids in hFABP7. (a) Comparison of the binding positions of PA, OA and DHA in the fatty acid-binding pocket in hFABP7. Inset: chemical structures of the bound ligands in hFABP7. (b) Comparison of the packing of PA, OA and DHA into the FA-binding pocket of hFABP7. The deeper hydrophobic pocket and β5–β6 pore are indicated by a yellow dotted outline and a blue arrow, respectively. (c) Comparison of the interaction of PA, OA and DHA with hFABP7. (d) Superimposition of the binding site for the carboxylate in FAs. Spheres represent water molecules. (e) Superimposition and comparison of PA, OA and DHA molecules in hFABP7.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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