Figure 1
(a) Sequence alignment and (b) overlap of PDB entries 2wce (blue), 1k9p (yellow) and 1k96 (brown), showing the domain movement between PDB entries 2wce and 1k96. (c) The difference electron density for Thr43, missing from the search model, after initial refinement to R and Rfree factors of 46% and 49%, respectively. (d) Final electron-density map for Thr43 after Buccaneer rebuild: R = 22% |