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Figure 4
Arrangements of strands in some β-sandwiches containing β-links. Diagrammatical representations are shown (af), with corresponding illustrations as ribbon models (gl). In the diagrams the two layers of the sandwich are coloured salmon and blue, while the β-links are red: the β-turn is indicated by a kink and the line representing the singleton of the β-bulge is shorter. In the ribbon models the colour scheme is similar to that in Fig. 3[link](a). (a) The simplest situation, in which each sheet has the same number of antiparallel strands and the two upper strands are connected between both sheets. (b) As (a), but with an additional strand (dark grey) in the back sheet separating the two upper strands that are adjacent in the front sheet. (c) As (a), but with an additional shorter strand (dark grey) above what was previously the upper strand. (d) Second (singleton) strand of the motif not connected directly to the back sheet. (e) With a second β-link (2) oriented in the opposite direction on the back sheet. (f) With a second β-link (2) lying between the same pair of strands in the same sheet as the first β-link, but oriented in the opposite direction. (g) Tendamistat, a bacterial α-amylase inhibitor (PDB entry 1bvn; Wiegand et al., 1995BB46): SCOPe domain d1bvnt_, b.5.1.1. (h) CD2 binding domain of CD58 (PDB entry 1ccz; Ikemizu et al., 1999BB21): SCOPe domain d1ccza1, b.1.1.1. The additional strand corresponding to that in (b) is marked with an arrowhead. (i) Charcot–Lyden crystal protein (PDB entry 1lcl; Leonidas et al., 1995BB32): SCOPe domain d1lcla_, b.29.1.3. The additional strand corresponding to that in (c) is marked with an arrowhead. (j) TNF receptor ligand (PDB entry 2q1m; Chattopadhyay et al., 2007BB9): SCOPe domain d2q1ma1, b.22.1.1. The continuation of the second strand of the β-link is marked with an arrowhead. (k) Probable antibiotic synthesis protein TTHA0104 (PDB entry 1v70; Yokoyama et al., 2008BB48): SCOPe domain d1v70a_, b.82.1.9. (l) Plastocyanin (PDB entry 3cvb; Crowley et al., 2008BB12): SCOPe domain d3cvba_, b.6.1.1.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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