Figure 4
Domain comparison between the inactive and activated VanRSc structures. Inactive VanRSc is shown in yellow and activated VanRSc is shown in slate blue. (a) Superposition of the receiver domains; the largest differences are the lack of α4 in the inactive state and changes in conformation of the β4–α4 loop. (b) Superposition of the DNA-binding domains; the only significant difference between these two structures is the conformation of the α7–α8 loop. |