view article

Figure 2
Examples of biologically relevant photocaged small molecules for which rates of photo-decaging have been reported. The compounds are ordered so as to facilitate comparison between similar scaffolds. Color-coding indicates compound classes: o-nitrobenzyl (red), red-shifted o-nitrobenzyl (orange), nitrodibenzylfuranyl (yellow), p-hydroxyphenyl (green) and coumarinyl (blue). Each plot gives values for five properties: maximum absorption wavelength (λmax), extinction coefficient at λmax (ɛmax), cleavage rate, quantum yield (φ) and a qualitative assessment of the expected solubility. The photo-released groups are highlighted in bold. The point of photocage attachment for each compound is phosphate (ATP), γ-carboxylate or amine (Glu), or ether (EGTA), as shown in Fig. 3[link].

Journal logoSTRUCTURAL
ISSN: 2059-7983
Follow Acta Cryst. D
Sign up for e-alerts
Follow Acta Cryst. on Twitter
Follow us on facebook
Sign up for RSS feeds