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![[Figure 2]](qt5001fig2mag.jpg)
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Figure 2
Correlative cryo-SXT and representative infrared and visible maps of control cells and HCV-replicating cells. (a, e) Three-dimensional reconstruction of whole-cell volumes of control and HCV replicon-bearing cell lines by cryo-SXT. Tile-scanned projections showing the area selected for SXT as well as volume tomograms are shown. A colour-coded manual segmentation of the surface boundaries identifying different organelles is presented. The normal mitochondria are segmented in green, abnormal mitochondria type I are segmented in red, abnormal mitochondria type II are segmented in purple, ER is segmented in yellow, modified ER is segmented in brown and nuclear envelope is segmented in pink. (b, f) Lipid area distribution, (c. g) Amide I area distribution. (d, h) Absorbance ratios corresponding to oxidation (A1740/A2960+2925). Blue is low intensity, red is high intensity. The scale bar represents 1 µm |
![[Figure 2]](qt5001fig2.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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