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Figure 3
The backbone structure of the H-HEWLEC Lys97–Gly104 loop (extended to Ala107) is considerably different from those of D-HEWLEC, H-HEWL and of HEWL in different crystal systems. PDB entries 2vb1, 1iee, 3wl2 and 6f1o were chosen as representative of native H-HEWL crystallized in the triclinic, tetragonal, monoclinic and orthorhombic systems, respectively. The Lys97–Ala107 regions of the different variants were structurally aligned; for clarity, only the main-chain atoms are shown. This illustration was produced using PyMOL (version 2.0; Schrödinger).

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 77| Part 12| December 2021| Pages 1579-1590
https://doi.org/10.1107/S2059798321010950
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