Figure 4
The single Glu7 conformation present in H-HEWLEC. The 2Fo − Fc electron-density map shown was contoured at 2σ (a) and the respective hydrogen-bond interactions with Lys1 Nζ, Gly4 N and Val2 O are depicted in (b). W314 mediates the interaction between Glu7 and Val2 through hydrogen bonds. This illustration was produced using PyMOL (version 2.0; Schrödinger). |