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Figure 5
Assessment of modeled interfaces in SARS-CoV2 cryo-EM assemblies. (a) Distribution of PI-score for the SARS-CoV-2 assemblies. (b) Plot of PI-scores (averaged over all interfaces within a structure) against the resolution of the structures. (c) Modeled interface between chain B (spike) and chain E (heavy chain of the antibody) in one of the open-state structures (PDB entry 7cac; 3.55 Å resolution) which was scored negative. (d) Re-refined structures for chains B and E of PDB entry 7cac, obtained using Coot real-space refinement, show improved shape complementarity of the protein–protein interface.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 78| Part 2| February 2022| Pages 152-161
https://doi.org/10.1107/S205979832101278X
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