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Figure 1
Overview of IDP/IDR data and the respective databases. The databases are organized according to the type of IDP/IDR data stored: sequence, binding regions and structural data. In the top part, examples are shown for each category using part of the N-terminal region of the human p53 protein (UniProtID p04637), its MDM2-binding short linear motif (ELM accession ELME000184 and PDB entry 1ycr, chain B, red) and the corresponding structural ensemble (PED ID PED00037e000). Curated databases are indicated with a check mark, deposition databases with a database icon and databases with predicted data with a machine-learning icon. Databases aggregating data from different sources have a light blue background. Created with BioRender (https://biorender.com/). |
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