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Figure 1
The structures of epibatidine, nicotine and analogues 16 used in this work. In all cases the protonated form, which is most likely under physiological conditions, is shown. The first aromatic ring after the azabicycloheptane (a fluoropyridine) is labelled A and the second ring labelled B is a benzylcarboxamide in compound 1 and a pyridinecarboxamide in compounds 26.

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ISSN: 2059-7983
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