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Figure 1
The structures of epibatidine, nicotine and analogues 1–6 used in this work. In all cases the protonated form, which is most likely under physiological conditions, is shown. The first aromatic ring after the azabicycloheptane (a fluoropyridine) is labelled A and the second ring labelled B is a benzylcarboxamide in compound 1 and a pyridinecarboxamide in compounds 2–6.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 78| Part 3| March 2022| Pages 353-362
https://doi.org/10.1107/S2059798322000754
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