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Figure 3
Loop C of AcAChBP adopts different conformations. Ribbon representation of loop C segments with the bound agonist epibatidine (cyan, PDB entry 2byq; Hansen et al., 2005BB20), antagonist strychnine (grey, PDB entry 5o8t; Dawson et al., 2019BB13) and the AcAChBP–1 and AcAChBP–3 complexes (red and black, respectively). Compound 3 is shown and coloured with the following scheme: C, black; O, red; N, blue; F, dark green. The overlay was calculated using all Cα atoms of a single subunit.

Journal logoSTRUCTURAL
ISSN: 2059-7983
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