Figure 1
Domain structure and overlay of individual domains with previous high-resolution structures. (a) Domain structure of InlB. The amino-acid numbers shown above indicate domain boundaries. The internalin domain consists of three structural regions: cap, LRR and IR. (b, c) Chains A, B and C of InlB392_wt are shown in dark blue, blue and cyan, respectively. Crystal forms I and II of InlB392_T332E are shown in green and dark green, respectively. Reference structures are shown in grey. (b) The internalin domains of all InlB392 structures were overlaid on PDB entry 1h6t. The overlay was performed for the LRR region. (c) The B repeat of all InlB392 structures was overlaid on chain A of PDB entry 2y5p. The red spheres indicate the Cα atoms of the residues before (residue 353) and after (residue 373) the region that is not resolved in chain C of InlB392_wt. |