Figure 1
Sequence alignment of RNase HI from E. coli and human and the reverse transcriptase from human immunodeficiency virus (HIV). The secondary-structure depiction is based on the crystal structure of E. coli RNase HI (PDB entry 2rn2). Alignment was performed with Clustal Omega (Sievers et al., 2011) and the figure was prepared with ESPript 3.0. Residues involved in the DEDD motif and the conserved histidine residue are indicated by green and orange triangles, respectively. |