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Figure 1
Sequence alignment of RNase HI from E. coli and human and the reverse transcriptase from human immunodeficiency virus (HIV). The secondary-structure depiction is based on the crystal structure of E. coli RNase HI (PDB entry 2rn2). Alignment was performed with Clustal Omega (Sievers et al., 2011 ) and the figure was prepared with ESPript 3.0. Residues involved in the DEDD motif and the conserved histidine residue are indicated by green and orange triangles, respectively. |


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