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Figure 2
(a) X-ray crystal structure of clorsulon bound to hCA I (PDB entry 7plf). (b) Clorsulon inside the active site of hCA I. Hydrophobic (red) and hydrophilic (blue) residues are labeled. (c) 2FoFc electron-density map of clorsulon bound to zinc in the hCA I active site contoured at the 1.0σ level. Residues involved in the binding of inhibitors are also shown; the gray sphere represents the Zn atom in the active site of the protein.

Journal logoSTRUCTURAL
ISSN: 2059-7983
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