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Figure 3
(a) X-ray crystal structure of clorsulon bound to SmCA (PDB entry 7pri). (b) Clorsulon inside the active site of SmCA. Hydrophobic (red) and hydrophilic (blue) residues are labeled. (c) 2FoFc electron-density map of clorsulon bound to zinc in the SmCA active site contoured at the 1.0σ level. Residues involved in the binding of inhibitors are also shown and the gray sphere represents the Zn atom in the active site of the protein.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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