view article

Figure 4
Comparison between new-inactive (green) and active (light magenta) Mpro. In the new structure the side chain of His163 rotates away to avoid steric clashes with the oxyanion loop: in the active conformation (PDB entry 6y2e) the His163 side chain would be 1.2 Å from the new position of Gly143 CO. Note also the movement of His172.

Journal logoSTRUCTURAL
ISSN: 2059-7983
Follow Acta Cryst. D
Sign up for e-alerts
Follow Acta Cryst. on Twitter
Follow us on facebook
Sign up for RSS feeds