Figure 3
Comparison of different representations for a tetrameric membrane protein resolved by cryoEM. A GluA2 glutamate receptor (EMDB entry EMD-2680 and PDB entry 4uqj; Meyerson et al., 2014) is shown as part of a full simulation system with explicit waters, ions and lipid molecules (membrane) (a), as an anisotropic network model (ANM) embedded in a membrane lattice that is also treated as an ANM (b) and as a set of pseudoatoms fitted using the TRN algorithm for vector quantization (c). |