view article
Figure 3
Structural homology and surface representation of the enclosed cavities in MSMEG_0317Δ. (a) Comparison of the MSMEG_0317Δ fold with the CD36 superfamily of scavenger receptor proteins, including the human lysosomal integral membrane protein 2 (LIMP-2) and CD36, a fatty-acid transporter, which show an extended asymmetric β-barrel core. (b) Comparison of the MSMEG_0317Δ enclosed cavities with the CD36 cavity which binds palmitic acid. (c) Close-up of MSMEG_0317Δ cavity 1 entrance 1. (d) Close-up of MSMEG_0317Δ cavity 1 entrance 2. (e) Close-up of MSMEG_0317Δ cavity 2. Hydrogen-bond and salt-bridge interactions are shown as black dashed lines. See also Supplementary Fig. S5.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 78| Part 4| April 2022| Pages 494-508
https://doi.org/10.1107/S2059798322001772
Follow Acta Cryst. D
Sign up for e-alerts
E-alerts
Follow Acta Cryst. on Twitter
Twitter
Follow us on facebook
Facebook
Sign up for RSS feeds
RSS