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![[Figure 4]](jb5039fig4mag.jpg)
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Figure 4
The crystal structure of xenon-derivatized MSMEG_0317Δ (referred to as MSMEG_0317Δ-Xe). (a) Comparison of the crystal structures of monomer 1 and monomer 2 of MSMEG_0317Δ with MSMEG_0317Δ-Xe. The positions of the five Xe atoms (Xe 1 to Xe 5) in monomers 1 and 2 of MSMEG_0317Δ-Xe are highlighted. The disordered loops 6 and 9 are shown as dotted lines. (b) Overlay of the crystal structure of MSMEG_0317Δ with MSMEG_0317Δ-Xe and close-up view of the base of the β-barrel core to highlight conformational flexibility near the region of loop 3, the α2 turn, loop 11 and loop 9. Loop 9 adopts a closed conformation in MSMEG_0317Δ, while in MSMEG_0317Δ-Xe loop 9 is disordered (dotted line). Hydrogen-bond interactions are shown as black dashed lines and van der Waals interactions are shown as red dashed lines. See also Supplementary Fig. S6. |
![[Figure 4]](jb5039fig4.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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