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Figure 3
Model fit results for csMSP1E3D1 nanodiscs. (a) Global fit to experimental SAXS data sets from frames with increasing elution volumes/positions across the SEC peak. Data sets are the middle eight highlighted frames in Fig 2[link](a). (Individual fits are shown in Supplementary Fig. S3.) The topmost data set is on an absolute scale, while those below are scaled by 2−n, where n is the frame number. (b) Refined structural parameters. The coloured data points indicate parameters refined from each data set individually. The black lines indicate parameters refined from the global fit, where one shared value is found for AL, vP and vL, while NL and ɛ are both forced to follow a linear trend. (c) Representation of the nanodisc model used; a quarter of the MSP belt is not shown to highlight the interior structure of the lipid bilayer.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 78| Part 4| April 2022| Pages 483-493
https://doi.org/10.1107/S2059798322001838
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