Figure 5
Superposition of chain A of the different structures, showing the molecules bound in the catalytic cleft of WT and C54S mutant SmeCOSe species. Sulfate-bound WT SmeCOSe (PDB entry 6g5z) is shown in pink tones, choline-bound WT SmeCOSe (PDB entry 6g60) in dark green tones, choline-bound C54S SmeCOSe (PDB entry 7pth) in light green tones and choline-bound C54S SmeCOSe (PDB entry 7ptj) in orange tones. The catalytic metal cation (Me) is also shown in green. |