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Figure 1
The hexameric structure of MDCC–Hsp90αMC. (a) The hexamer is shown in cartoon representation and is colored green (chain A), cyan (chain B), magenta (chain C), yellow (chain D), orange (chain E) and gray (chain F). MDCC molecules are shown as spheres and are located at the hexamer interface. (b) Structural alignment of the monomer of chain C (magenta) in MDCC–Hsp90αMC (MDCC is shown as yellow sticks) with that in the apo structure (PDB entry 3q6n, cyan). The three ordered loops, the catalytic loop, Src loop and CTD loop, are indicated.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 78| Part 5| May 2022| Pages 571-585
https://doi.org/10.1107/S2059798322002261
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