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Figure 4
Active-site structure of PvSAE. (a) Active-site overlay of Apo I PvSAE and pAF-AH (PDB entry 3dt9), with active-site residues and soman inhibitor shown as sticks. PvSAE residues are labelled in black and pAF-AH residues are labelled in blue. Polar contacts between the soman inhibitor and active-site residues are displayed with black dashed lines. pAF-AH and soman inhibitor C atoms are coloured purple, while PvSAE C atoms are coloured green. (b) Active-site overlay of PvSAE and NanS (PDB entry 3pt5; Rangarajan et al., 2011 ![]() |