Figure 1
Crystal packing and peptide arrangement. (a) The asymmetric unit consists of two peptide molecules (labeled Pep and Pep*; purple and pink, respectively) packed between two MagaFab molecules (MagaFab molecule 1 light chains labeled VH/VL; MagaFab molecule 2 light chains labeled VH*/VL*). A third neighboring VL chain (orange, not labeled) from a different asymmetric unit establishes weak interactions with one of the peptides. (b) Electrostatic surface showing polar pockets for the peptide interaction and important structural waters. Red indicates a negatively charged surface, while blue indicates positive charge. |