LRG1 models. (a) Superposition of a homology model of LRG1 (red, predicted with SWISS-MODEL) and NetrinG ligand 2 (NGL2; PDB entry 3zyi, chain A) used as the template. The arrow shows the location of the epitope recognized by MagaFab (black, LRR7). Leucine-rich repeats 1, 7 and 9 are labeled as a reference. (b) Superposition of the LRG1 homology model (red), the best threading model (blue) and the ab initio model predicted by AlphaFold (yellow). Leucine-rich repeats 1, 7 and 9 are labeled as a reference and the signal peptide is labeled SP.