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Figure 5
MagaFab–LRG1 complex. (a) Superposition of the LRG1 model (green) with the crystal structure of the peptide (violet) and MagaFab (orange), taking the Cα atoms of Gln225 and Val226 as a reference, including a 90° side view. A flexible and exposed loop of MagaFab that is potentially involved in LRG1 recognition is labeled with a star. (b) The superposition of LRG1 LRR7 with the peptide of the crystal structure shows significant conformational differences in the main chain, probably not only due to the already described crystal contacts with the peptide but also due to inaccuracies in the LRG1 homology model.

Journal logoSTRUCTURAL
ISSN: 2059-7983
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