Figure 3
(a) Improvement of phasing success with the introduction of an isomorphous term in the genetic algorithm fitness function for insulin I. The frequency of the CC of the partial model is shown for wiso of 0, 1, 10, 100, 1000 and 10 000. Average chain lengths of <11 residues per chain are shown in red and those of ≥11 are shown in cyan. (b) Experimental electron density from SHELXE contoured at 1.5σ. |