Figure 1
The domain architecture of CbpD and representative domain structures. CbpD is composed of three domains: an AA10 domain (green), a GbpA2 domain (yellow) and a CBM73 domain (red). The domain structures of the AA10 and GbpA2 families are represented in the crystal structure of V. cholerae GbpA (PDB entry 2xwx), while the domain structure of the CBM73 family is represented in the NMR solution structure of CjLPMO10A (PDB entry 6z40). Hashes represent regions that are not included in the constructs used in the cited structural studies. Dashed orange lines encapsulate the domain(s) resolved in the respective reported structures. Residue boundaries for each domain are labeled based on previous annotations, adjusted so that the N-terminal His in each mature protein is residue 1. |