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![[Figure 4]](ni5021fig4mag.jpg)
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Figure 4
Formation of the RBD Q498Y–ACE2 complex. (a) The elution profile of RBD Q498Y alone (orange trace) or complexed with ACE2 (blue trace) was monitored to track the proper formation of the complex through size-exclusion chromatography. The inset shows an image of crystals of the RBD Q498Y–ACE2 complex. mAU, absorbance units (×10−3). (b) Composition of the asymmetric unit in the RBD Q498Y–ACE2 crystal. All RBD and ACE2 molecules are shown as individual colored cartoons accompanied by a 2Fo − Fc electron-density map (gray) contoured at the 1.0σ level. |
![[Figure 4]](ni5021fig4.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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