view article
Figure 7
Kinetics and binding-affinity analysis of ACE2 with individual mutations found in the SARS-CoV-2 β VOC spike RBD. Biolayer interferometry analysis using ACE2 captured on the surface of an Ni–NTA sensor, as described in Fig. 2[link]. Increasing concentrations of RBD mutants K417N, E484K and N501Y were exposed to ACE2 in 20 mM HEPES pH 7.4, 150 mM NaCl. Red, experimental data; black, fitting of the experimental data to a 1:1 Langmuir model.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 78| Part 9| September 2022| Pages 1156-1170
https://doi.org/10.1107/S2059798322007677
Follow Acta Cryst. D
Sign up for e-alerts
E-alerts
Follow Acta Cryst. on Twitter
Twitter
Follow us on facebook
Facebook
Sign up for RSS feeds
RSS