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Figure 1
Human MPO crystallized in space group C2. (a) The greenish colour indicates the presence of Fe3+ in the heme. (b) Electron density for the heme group of MPO and the nearby binding of thiocyanate and paroxetine, as found in the monomer with chain ID A. Amino-acid numbering is based on the pro-MPO crystal structure numbering (Grishkovskaya et al., 2017BB21), including the signal peptide and pro-peptide. This figure was made using the CCP4MG molecular-graphics visualization program (version 2.11.0; McNicholas & Agirre, 2017BB35).

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 78| Part 9| September 2022| Pages 1099-1109
https://doi.org/10.1107/S2059798322007082
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