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![[Figure 2]](rr5223fig2mag.jpg)
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Figure 2
The eight monomers forming four biological assemblies (homodimers AB, CD, EF and GH) in the crystal structure of human MPO, with their glycosylation structures. Each chain has a different colour. Monomers A, D, F and H have a bound paroxetine inhibitor (magenta), and each catalytic site carries an iron-containing heme group (sea-green) and has an S-hydroxy-L-cysteine (yellow) within a distance of 12 Å from the heme group. All N-glycosylations start with an N-acetylglucosamine (blue square), modifying the labelled asparagine, and many are also further substituted with mannose (green spheres) and fucose (red triangles). This figure was prepared using CCP4MG (McNicholas & Agirre, 2017  ). |
![[Figure 2]](rr5223fig2.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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