view article
Figure 3
Hit identification and validation in the ATAD2 fragment campaign. (a) The low-c ITC thermogram and (b) the HTRF experimental assay design used in early-stage fragment hit validation. (c) The crystal structure of the elaborated fragment based on the initial validation results (PDB entry 7px5).

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 78| Part 11| November 2022| Pages 1294-1302
https://doi.org/10.1107/S2059798322009986
Follow Acta Cryst. D
Sign up for e-alerts
E-alerts
Follow Acta Cryst. on Twitter
Twitter
Follow us on facebook
Facebook
Sign up for RSS feeds
RSS