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Figure 2
The crystal structure of the Drosophila frataxin homolog Dfh. (a) Ribbon structure and (b) surface electrostatic potential plots for Dfh at three different orientations around the vertical axis. (a) Labels for the different secondary-structural elements are marked on the corresponding helix or strand (PDB entry 7n9i). (b) To the left is a surface electrostatic potential plot for Dfh in an orientation that corresponds to the ribbon structure. Electrostatic surface plots were calculated using PDB2PQR and are labeled with the APBS plugin for PyMOL using a solvent radius of 1.4 Å and a contour value of 10 kT e−1 for both charged isoforms. Secondary-structural landmarks on the rotated structures are labeled for clarity. |