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Figure 5
STD-NMR results for Aurora-A and ANX with ADP alone and mixed with MK-5108. On the left, 1H peaks at 8.45 and 8.20 p.p.m. can be seen in the difference spectra, which show saturation transfer from the respective protein to ADP. On the right, no saturation difference occurs since MK-5108 blocks the nucleotide binding site. Off-resonance spectra are shown in Supplementary Figs. S1 and S2.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 79| Part 1| January 2023| Pages 1-9
https://doi.org/10.1107/S2059798322011433
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