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Figure 5
Comparison of AAV5 (green) and AAV4 (orange) at selected variable regions (VR) where PKD1 (yellow) interacts with AAV5. Amino-acid sequence alignments for each VR are provided below the set of structures, with numbers showing the first and last residues of the VR (according to VP1 numbering); residues of interest extending beyond the variable region are supplied after the number; contact residues are shown in green, while clashing residues are shown in red. Residues extending beyond VR-IX are shown in the VR-IX alignment. Residues of interest are labeled on the structures and underlined in the alignment. The clash between AAVR and AAV4 for VR-VII is surrounded by a circle to highlight its presence.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 79| Part 2| February 2023| Pages 140-153
https://doi.org/10.1107/S2059798322012190
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