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![[Figure 1]](vo5012fig1mag.jpg)
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Figure 1
Docked models in maps for challenging cases. Both maps are computed using the Fourier coefficients ![[{\bf F}_{\rm map} = [2/(1 - D_{\rm obs}^2\sigma_{\rm A}^2)]D_{\rm obs}\sigma_{\rm A}{\bf E}_{\rm mean}]](teximages/vo5012fi3.svg){kind=small} arising from analysis of the local map volumes and the images were made with ChimeraX (Goddard et al., 2018 ). (a) Chain M (magenta) of PDB entry 3rko docked into the region of the map corresponding to chain M of PDB entry 7nyu (associated with EMDB entry EMD-12654). Chain N is shown in light blue. (b) The AlphaFold model of the smallest domain of the ΔF508 mutant of CFTR (magenta) docked into the corresponding region of the map derived from EMDB entry EMD-28172. The membrane domain is shown in light blue. |
![[Figure 1]](vo5012fig1.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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