Conformational transition of the Ixodes ricinus salivary serpin Iripin-4

Kascakova, B.; Kotal, J.; Havlickova, P.; Vopatkova, V.; Prudnikova, T.; Grinkevich, P.; Kuty, M.; Chmelar, J.; Kuta Smatanova, I.

doi:10.1107/S2059798323002322

Acta Crystallographica Section D
Acta Crystallographica
Section D STRUCTURAL BIOLOGY

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Figure 5
Structural superposition of Iripin-4 conformations. The native Iripin-4 (cyan) with an exposed RCL (blue) is aligned with cleaved Iripin-4 (grey) containing a new additional β-strand (marine) labelled s4A. The three regions responsible for insertion of the RCL into β-sheet A are marked in circles (Khan et al., 2011

). The hinge region is marked with an oval.

STRUCTURAL
BIOLOGY

ISSN: 2059-7983

Volume 79| Part 5| May 2023| Pages 409-419

https://doi.org/10.1107/S2059798323002322

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