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Figure 8
(a) Overlay of insulin structures in a variety of T-like states. (b) Root-mean-square fluctuations of the Cα position during coarse-grained molecular-dynamics simulations. Blue, polycrystalline cubic structure (PDB entry 7qac); purple, single-crystal cubic structure (PDB entry 3i40); pink, rhombohedral T6 structure (PDB entry 1mso); green, orthorhombic AlaB8NMeAla T2 structure (PDB entry 4cy7); yellow, orthorhombic SerB9Glu T2 structure (PDB entry 1b9e).

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ISSN: 2059-7983
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