Structural and functional investigation of a fungal member of carbohydrate esterase family 15 with potential specificity for rare xylans

Mazurkewich, S.; Scholzen, K.C.; Brusch, R.H.; Poulsen, J.-C.N.; Theibich, Y.; Hüttner, S.; Olsson, L.; Larsbrink, J.; Lo Leggio, L.

doi:10.1107/S205979832300325X

Acta Crystallographica Section D
Acta Crystallographica
Section D STRUCTURAL BIOLOGY

IUCr IT WDC

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Figure 5
Close-up of the extra cavity in LfCE15C where additional hemicellulose decorations could be accommodated. LfCE15C is shown as a surface with the overlaid structure of CuGE (PDB entry 6rv9). Only the bound XUXXr and Glu324 (a glycine in LfCE15C) are shown for CuGE. Possible attachment sites for additional decorations are indicated by the black arrow (O2 arabinose decoration on the xylan backbone) and blue arrow [a rare pentose decoration on GlcA as reported by Mortimer et al. (2015