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Figure 8
Positioning of the substrate relative to the catalytic Lys258 and the possibly catalytic Glu200. (a) Superposition of bound Trp (orange C atoms) and 5-Br-Trp (dark green C atoms) with Glu200 and Lys258 from the same structure in yellow and green, respectively. In each case the catalytically preferred C atom points towards the (possibly) catalytic amino acids. (b) Bound Trp (orange C atoms) from PDB entry 8cje chain A. Distances to the catalytically preferred position C5 are shown as grey dashed lines and are given in Å.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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