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Figure 9
The tunnel connecting FAD and substrate. AetF is shown as a cartoon (domains coloured as in Fig. 2[link]) in complex with FAD (yellow C atoms) and Trp (orange C atoms). CAVER 3.0 revealed a narrow tunnel (red surface) connecting FAD and Trp, which presumably allows diffusion of HOX from the cofactor to the substrate. The catalytic Lys258 is shown as sticks (magenta C atoms).

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ISSN: 2059-7983
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