Figure 7
Example of the interactive selection of particle views providing more information on the 3Down to 1Up conformational change of the spike. From the original 3D conformations, a rotation–tilt heatmap is computed determining how good each combination of angles is at distinguishing between the two conformations analysed. In the heatmap, red colours correspond to the regions where the 1Up and 3Down conformations are better discriminated (i.e. the simulated projections differ the most). The color map represents the Pearson correlation values estimated from the simulated projections. |