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Figure 3
NADPH binding site and comparison to closely related enzymes. (a) Superimposed image of the NADPH binding site of the ternary complex of CauDHFR with NADPH and PYR (white; residues of interest are labelled in green; PDB entry 8a0z) and the CauDHFR apoenzyme (cyan, PDB entry 7zzx). (b) Superposition of the NADPH binding sites of the ternary complex of CauDHFR with residues of interest displayed (green; PDB entry 8a0z), CalDHFR (pink; PDB entry 3qlw) and CglDHFR (orange; PDB entry 3qlz).

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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